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Hormone Therapy

Success of abiraterone trials prompts ‘mind shift’ in prostate cancer treatment

November 5, 2017

Abiraterone acetate is poised to challenge docetaxel as the standard addition to androgen deprivation therapy for treatment of newly diagnosed, metastatic castration-resistant prostate cancer. Read the article here.

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Prostate cancer: Could a breast cancer drug reduce recurrence

November 5, 2017

A new study suggests that combining a breast cancer drug with hormone therapy could be a more effective strategy to reduce the progression and recurrence of prostate cancer in men. Read the article here.

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Abiraterone Delays Metastatic Prostate Cancer Growth by 18 Months, Extends Survival

July 2, 2017

Adding abiraterone acetate (Zytiga) plus prednisone to standard hormonal therapy for men newly diagnosed with high-risk, metastatic prostate cancer lowers the chance of death by 38%. In a phase III clinical trial of 1,200 men, abiraterone also more than doubled the median time until the cancer worsened, from 14.8 months to 33 months. Read the […]

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Biolyse Pharma stymied in effort to make cheaper version of pricey prostate cancer drug

April 9, 2017

A small Canadian company has waded into a U.S. drug price controversy by offering to make an expensive prostate cancer drug for a fraction of the price. Right now Xtandi costs U.S. patients as much as $129,000 US a year, or about $90 per pill. St. Catharines, Ont.-based Biolyse Pharma says it can make the […]

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Psychological Effects From ADT a Growing Challenge in Prostate Cancer

February 19, 2017

Androgen-deprivation therapy (ADT) can be associated with significant psychological effects in patients with prostate cancer. Additionally, these side effects—which include depression, Alzheimer disease, and coronary disease—are often under-reported by patients. Read the article here.

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Prostate Cancer Treatment Can Raise Dementia Risk

February 19, 2017

Reducing testosterone levels with androgen deprivation therapy, or A.D.T., is a common treatment for prostate cancer. But a new study has found that it more than doubles the risk of dementia. Read the article here.

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ADT May Increase Depression Risk in Prostate Cancer

July 3, 2016

When elderly men with localized prostate cancer are given androgen-deprivation therapy (ADT), the risk of depression and hospitalization for psychiatric treatment is significantly increased, a population-based study of 78,000 U.S. men showed. Read the article.

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Common prostate cancer treatment may double Alzheimer’s risk

March 6, 2016

The results of a study support an association between the use of androgen deprivation therapy (ADT) in the treatment of prostate cancer and an increased risk of Alzheimer’s disease in a general population cohort. Read the article.

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Video: Dr. Shabbir Alibhai, “Understanding, preventing and managing side effects of hormone therapy.”

March 4, 2016

January 2016 Awareness Night   Understanding, preventing and managing side effects of hormone therapy. Dr. Shabbir Alibhai,MSc, MD, FRCPC,Princess Margaret Cancer Centre Senior Scientist, Toronto General Research Institute (TGRI) Scientist, Toronto Rehabilitation Institute (TRI) Asst Prof, Depts of Medicine and Health Policy, Management, and Evaluation at the U of Toronto CLICK ON THE ARROW TO […]

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Prostate cancer survivors more likely to die of other diseases

February 15, 2016

Prostate cancer survivors are most likely to die from something other than cancer, with cardiovascular disease as the most common cause, according to a new study. Androgen deprivation therapy, or ADT, may increase several cardiovascular risk factors that contribute to heart disease and adverse cardiovascular events, researchers at Vanderbilt University report. Read the article.

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